As ever in a cup match you always have to consider who the game means more to. Napoli top Serie A and while Lazio are very much in the title race, they are at home and have plenty of injuries so might not have the ability to rotate as many as Napoli will.

These two also meet in the league on Sunday so Napoli might not want to show their hand. They made wholesale changes in the last round and could do the same here, so a potentially stronger Lazio side can avoid defeat in 90 minutes.

Lazio have won the third most corners in Serie A this season and with their starting XI expected to be stronger than the Napoli one and therefore potentially more in sync, at least from the beginning, expect Lazio to win the most corners here.

Lazio won a huge 10 corners in defeat to Parma at the weekend and anything close to that number should see them win the most here at a nice price.

One man who might be in the Lazio side for this match is midfielder Nicolo Rovella, who is suspended for the Serie A match at the weekend.

He comes into this game off the back of 3 shots in the defeat to Parma on Sunday and with him likely to get 90 minutes, he feels like a good option to get a shot away for the home side here at a solid price.

With Napoli expected to rotate their team and Lazio short of options to change things up, a high scoring clash probably isn’t on the cards here. It rarely is when these two meet.

None of the last 5 between the pair have had more than 3.5 goals in them and with Napoli defensively solid but likely to rotate their front three, this doesn’t feel like a game which will explode into life.

Lazio are not expected to make changes for this match and one man could come in is the young French player Loum Tchaouna – and he looks a big price to score.

He has scored once in just 215 minutes in Serie A this season, but with the chance to shine here, the forward can threaten against a rotated Napoli side at a big price.

The striker is averaging 5 shots per 90 and 2.08 shots on target per 90 in Serie A this term and could find the net here.

With Napoli expected to make changes as they did in the previous round and Lazio not really having the ability to do that even if they wanted to with the injuries they have, particularly in the centre of the pitch, it makes sense to take the home side to qualify.

Prior to their defeat to Parma at the weekend, Lazio had won their last 5 in Serie A and are 6-1-0 at home this season, so should be taken to get the better of Napoli at some point in the night.

Matches between these two tend to be fairly tight affairs and with the attentions of both of them likely to be on other competitions and the evening largely about giving game time to those who might need it, it is hard to see this one igniting into life to have 4 goals in it.

Napoli have only conceded 9 goals in 14 games in Serie A and aren’t free scoring either. With rotated personnel in key positions 4 goals feels unlikely here.

Scott McTominay is the joint third highest scorer for Napoli in Serie A this season and is likely to be one of the few players who remains in the side for this match.

He scored in the previous round and is no stranger to either a pot shot from distance or getting on the end of something in the box.

With the likes of Romelu Lukaku and Khvicha Kvaratskhelia likely to be rested, the best value for a shot in the visiting side could well lie with the Scotland international who averages 2.06 shots per 90 in Serie A this term.