Fiorentina v Real Betis

Real Betis come into this fixture with a much-needed one-goal cushion after achieving victory in Seville last Thursday. They have won their last four matches, including a notable 5-1 victory against Real Valladolid in the league.

Fiorentina, who have been the competition's runners-up in each of the previous two seasons, come into this clash after suffering back-to-back defeats despite being undefeated in nine consecutive games prior to their first-leg defeat.

With both sets of eyes firmly set on the trophy, the challenge only further intensifies in Florence, as the road to Warsaw approaches its finale.  

⭐ Fiorentina v Real Betis Best Bets

➡️ Back Fiorentina Double Chance with bet365 @ 1.36

Although Fiorentina are more than capable of turning the tie around, a double chance pick (win or draw) offers a smarter and more pragmatic approach in what promises to be a closely contested second leg. La Viola is unbeaten in their last seven home matches (W5, D2) and have shown they can rise to the occasion in Florence, including a dramatic 3-1 home win against Panathinaikos earlier in the competition (overturning a 3-2 deficit in the away first leg).

However, Real Betis are not a team easily undone — they’re on a four-match winning streak and have gone unbeaten in their last eight away games (W6, D2), including an impressive record of scoring first in 11 of their last 12 Conference League matches. 

While that consistency makes them a difficult team to eliminate, it also increases the likelihood of a cagey, possibly drawn match where Betis simply protect their aggregate advantage.

Fiorentina, meanwhile, are under pressure to push for qualification, but their recent back-to-back losses, including defeat to Roma on the weekend, hint at possible vulnerability if they overcommit. A draw or narrow win may be within reach without necessarily guaranteeing progression, making the double chance a more secure and value-conscious selection.

This pick balances Fiorentina’s strong home form with the resilience and momentum of Betis, recognising that while La Viola may not go through, they’re well-positioned to avoid defeat in 90 minutes.

👕 Fiorentina v Real Betis Predicted XI

🔍 Fiorentina v Real Betis Players to Watch

🟢 Isco

A creative maestro in possession, Isco’s off-ball discipline remains a vulnerability. He averages 1.62 fouls per 90 this season, but that figure rises to 2.57 solely in European action. He has committed 2+ fouls in each of his last five continental starts and nine of his last 12 matches overall.

With Betis likely to protect their lead and Fiorentina’s midfield drawing 16 fouls across their last four matches, Isco will likely be under persistent pressure.

➡️ Back Isco to Commit 2+ Fouls with bet365 @ 2.75 ↔️

🟣 Rolando Mandragora

Beyond his volume of attempts (averaging 1.87 shots per 90 in Europe), Mandragora’s end product has also impressed in Europe, scoring five of his eight goals this season in this competition. Notably, seven of his last eight goals have been either the first or second goal of the match, often setting the tone.

With Fiorentina needing goals, Mandragora’s long-range ability and tendency to strike early make him a strong outsider for a crucial goal here.

➡️ Back Rolando Mandragora to Score Anytime with bet365 @ 5.50 ↔️

📂 Fiorentina v Real Betis Cheat Sheet

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💻 Fiorentina v Real Betis Form and Tactics

Under Raffaele Palladino, Fiorentina have transitioned to a more pragmatic approach, emphasising defensive solidity and structured buildup play. Deploying a 3-5-2 formation, they focus on controlling the midfield and utilising wing-backs to provide width. This system aims to maximise possession and create overloads in central areas.

However, recent performances have highlighted challenges in converting possession into goals. In the first leg against Betis, Fiorentina struggled to cope with quick transitions, leaving spaces that were exploited by the opposition. Addressing these vulnerabilities will be crucial in the return leg.

Despite losing their last two matches, which includes a defeat to Roma over the weekend, Fiorentina had previously enjoyed a 10-match unbeaten run across all competitions. Notably, they remain unbeaten in their last seven home games (W5, D2), a record they'll aim to extend if they are to overturn their first-leg deficit.

Manuel Pellegrini's Real Betis have showcased a balanced tactical setup, blending disciplined defence with rapid offensive transitions. Operating primarily in a 4-2-3-1 formation, Betis emphasise compactness out of possession and swift counter-attacks. Key to their approach is the utilisation of players like Isco and Antony, who provide creativity and pace in the attacking third.

In the first leg, Betis effectively exploited spaces behind Fiorentina's wing-backs, capitalising on transitional moments to secure a 2-1 advantage. Their ability to adapt tactics mid-game and maintain defensive organisation has been instrumental in their European campaign.

Entering this second leg tie, Betis are in formidable form, having won their last four matches and remain unbeaten in their previous eight away games (W6, D2). This momentum, coupled with their tactical discipline, positions them well to secure a historic place in the Conference League final.

As the second leg approaches, Fiorentina will need to address their defensive frailties and enhance their attacking efficiency to overturn the deficit. Conversely, Betis will aim to maintain their tactical discipline and capitalise on counter-attacking opportunities to secure a historic place in the Conference League final.

🏁 Fiorentina v Real Betis Ref Watch

• Referee: Glenn Nyberg

• Stats are on a per 90 basis and are taken from Nyberg's 24/25 games across all competitions (13 total)

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* I recommend waiting for confirmed team line-ups before placing any bets.

* All odds displayed correct at the time of publishing.