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Bryan Mbeumo has been in decent goalscoring form so far this season, netting three goals across his six starts in the Premier League - with the latest goal coming against Tottenham at the weekend.

Mbeumo has always been a very solid finisher, and could find himself leading the line again here with Benjamin Sesko still being a doubt for the game. He registered an assist in United’s convincing 4-0 win over Sabah in thru first Champions League game and had one shot on target in that clash.

Mbeumo scored 11 goals in the Premier League last season, taking 73 shots across his 31 starts in the competition (2.51 per 90). 32 of these efforts found the target (1.10 per 90), which is a solid record over a decent sample size to suggest that Mbeumo will find the target at least once here.

Inter have started the season really well, winning five of their opening six matches in Serie A - scoring 18 goals in the process.

Only Roma, who sit just behind them in the table, have managed to take points off them domestically this season in the form of a 2-2 draw a few weeks back - Inter won the xG battle in that game too (2.86-1.66).

Inter did lose their opening game of their Champions League campaign, but you can’t get much tougher assignments in the Champions League than a trip to the Bernabeu, making this game look much more winnable on paper.

Club Brugge have also started the season well domestically but tend to struggle at this level, as shown by their 3-2 defeat at home on Matchday 1 to Aston Villa.

That game saw them concede an xG of 3.22 despite having 64% of the ball - showing how they aren’t at the level of get anything from this clash with Inter looking really strong so far this season.

Arsenal look a lot stronger than Lille on paper here, and it is likely to be one-way traffic. The Gunners accrued eight corners in their opening Premier League match against Coventry, before also landing this selection against Chelsea. Last season, they had an average of 5.75 corners per game across all competitions, rising to 6.0 when playing at the Emirates. 

Set pieces remain a significant part of Arsenal’s attacking approach, so they typically look to utilise width when their opponents sit deep. The hosts should dominate proceedings, forcing Lille into extended spells of defending their box. That should bring corners into the game.

Galatasaray have lost just one of their home games over the last year and should be able to offer a decent attacking threat to a Barcelona side who are scoring for fun themselves at the moment.

Barcelona have won each of their last five matches ahead of this clash, but have only managed to keep a clean sheet in one of these games. They conceded two goals in their opening game of the Champions League campaign, scoring seven in response as they beat Feyenoord comfortably.

Galatasaray have seen BTTS in three of their last five matches, and this angle is mainly backing them to score as Barcelona are as short as 1.11 to find the back of the net here. Barcelona don’t care too much about conceding shots and chances, giving Galatasaray the perfect scenario where they can get on the scoresheet.

It’s hard to make a case for either of these backlines at the moment, United conceded to 10 man Tottenham over the weekend to mark another game where they’ve failed to keep a clean sheet - only Sabah have failed to score against United so far this season.

Atletico Madrid have found clean sheets quite difficult to come by too, keeping just three shutouts this term - with two of those coming against sides that sit in the bottom five of LaLiga following the opening set of matches. 

They’ve seen BTTS in each of their last two matches ahead of this game, and also saw BTTS in their opening game of the Champions League campaign as they fell to a 2-1 defeat to Liverpool. 

Simeone is not quite the same defensively minded manager he is usually pinned as, he’s been willing to be more expansive over recent seasons which partly explains Atletico Madrid’s early record.

Bryan Mbeumo has been in decent goalscoring form so far this season, netting three goals across his six starts in the Premier League - with the latest goal coming against Tottenham at the weekend.

Mbeumo has always been a very solid finisher, and could find himself leading the line again here with Benjamin Sesko still being a doubt for the game. He registered an assist in United’s convincing 4-0 win over Sabah in thru first Champions League game and had one shot on target in that clash.

Mbeumo scored 11 goals in the Premier League last season, taking 73 shots across his 31 starts in the competition (2.51 per 90). 32 of these efforts found the target (1.10 per 90), which is a solid record over a decent sample size to suggest that Mbeumo will find the target at least once here.

Marc Pubill really struggled in Atletico Madrid’s opening game of the Champions League campaign, committing three fouls and collecting a yellow card as Atletico Madrid fell to defeat at Anfield - with Pubill accounting for a third of the total fouls that Atletico committed.

Pubill is expected to continue at right centre back here, pitting him directly against Matheus Cunha who will be a real handful for the Spaniard to contain given his already aggressive baseline. Pubill has committed six fouls across his five starts in LaLiga this season (1.34 per 90).

Cunha was back on the left hand side for United’s 1-1 draw against Tottenham last time out, and looked much more comfortable in that role as he registered an assist and was fouled three times.

Cunha is a really good player when it comes to winning fouls due to how he moves with the ball. He’s very fluid and has a consistent record over the last few seasons, averaging 1.94 fouls won per 90 across 29 starts in the Premier League last campaign.

Cunha was fouled twice in United’s 4-0 win over Sabah in their opening Champions League game and will be up against Marcos Llorente and Marc Pubill in this one. I’m more interested in his battle with Pubill rather than Llorente, but Cunha can force either to haul him down on a few occasions here.

You really have to feel for Senne Lammens as his good work in goal for United over the last year or so has largely gone unnoticed due to how poor their overall defensive record has been.

Lammens has been doing his bit, he’s already made 18 saves across six starts in the Premier League this season (3.0 per 90), yet has not been rewarded with a clean sheet across these games for his efforts.

Lammens was forced into making 79 saves across his 32 starts in the Premier League last season (2.47 per 90) with a save percentage of 66.9%. Atletico Madrid forced Alisson into three saves in their opening game of the Champions League, and should be able to do the same against a United backline that is really struggling.  

Luis Javier Suárez has been making headlines for more than just his goals at Sporting this season. The striker has already picked up five yellow cards across the domestic league and Champions League.

The reasons behind those bookings are particularly revealing: two for arguing, two for committing fouls and one for an off-the-ball incident.

There’s no questioning Suárez’s commitment. He even managed to pick up a booking in an international friendly. That intensity, combined with the pressure of a Champions League fixture, could make it even harder for the striker to keep his emotions in check. In his determination to help the team, he could easily cross the line.

Croatian referee Igor Pajač will take charge of the match, averaging more than four yellow cards per game. He has shown little hesitation in reaching for his pocket in Europa League qualifying this season, handing out 12 yellow cards across two matches. That record suggests he is unlikely to tolerate players who let their emotions get the better of them.

There aren’t many moves in football that make as much sense as Romero joining Atletico Madrid. 

It’s a transfer that has looked inevitable for the last few years with Romero being the perfect player to embody Simeone’s style of play. He’s already picked up one yellow card for his new side, with that caution coming against Real Madrid.

Romero was cautioned in both league meetings between Tottenham and Manchester United last season, actually being sent off in Tottenham’s 2-0 defeat at Old Trafford towards the end of last season.

Romero will be up against Bryan Mbeumo here with Benjamin Sesko suffering a recurrence of the injury that kept him sidelined at the start of the campaign. Mbeumo averaged 0.96 fouls won per 90 last season and will cause Romero issues as a makeshift striker.

Bruno Fernandes cut the same frustrated figure that’s followed him throughout his United career after United failed to beat 10 men for the second time this season in front of their own fans last time out. 

Fernandes has every right to feel a bit let down by his team mates, he’s been setting an unreal standard for the last few seasons but that hasn’t been matched by the players around him - often leaving Fernandes as the sole point of quality within this United side.

Fernandes has registered four goal contributions across his six starts in the Premier League already this season and also scored against Sabah in United’s opening game of the season in the Champions League. 

Atletico Madrid have only managed to keep three clean sheets this season, with two of those shutouts coming against sides that sit in the bottom five sides in LaLiga. United can cause them issues with their attacking quality and Fernandes is an obvious candidate to register a goal contribution.

Alvarez is yet to get going this season, but this is the perfect game to announce himself with a goal contribution following what was a very turbulent summer for the striker in which he was heavily linked with a move to Barcelona.

Alvarez really enjoyed playing in the Champions League for Atletico Madrid last season, registering 14 goal contributions across his 15 starts in the competition - only Kvaratskhelia, Mbappe and Kane registered more goal contributions than Alvarez in the Champions League last season.

Furthermore, Alvarez is lining up against a United side who have only kept one clean sheet this term - with that shutout coming against Sabah on Matchday 1. Alvarez registered an assist in Atletico Madrid’s opening game of the campaign against Liverpool, and I’m backing him to cause similar damage to their rivals.

Maguire has already collected two yellow cards across his six starts in the Premier League this season, and I think we’ll see the centre back struggle with the speed of Atletico’s frontline with Alvarez, Lookman and Kang In Lee set to be running at him here.

Maguire is really well suited to the English game with his ability in the air and surprising composure on the ball - but he’s not very quick or agile, which is where his game can come apart a bit against a side with the attacking quality of Atletico Madrid. His main opponent here is likely to be Julian Alvarez, who averaged 0.85 fouls won per 90 last season.

I’m more interested in Maguire’s battles with Lookman (1.25 fouls won per 90) and Lee (1.61 fouls won per 90) who will know that they have the beating of the United centre back and will relish the chance to drag him into wider areas where Maguire is naturally not as comfortable.

There aren’t many moves in football that make as much sense as Romero joining Atletico Madrid. 

It’s a transfer that has looked inevitable for the last few years with Romero being the perfect player to embody Simeone’s style of play. He’s already picked up one yellow card for his new side, with that caution coming against Real Madrid.

Romero was cautioned in both league meetings between Tottenham and Manchester United last season, actually being sent off in Tottenham’s 2-0 defeat at Old Trafford towards the end of last season.

Romero will be up against Bryan Mbeumo here with Benjamin Sesko suffering a recurrence of the injury that kept him sidelined at the start of the campaign. Mbeumo averaged 0.96 fouls won per 90 last season and will cause Romero issues as a makeshift striker.

Viktor Gyokeres hasn’t been given much of a chance in the league this season, but the Swedish international is expected to start midweek to allow Kai Havertz a rest.

During the international break, Gyokeres was in exceptional form, and he scored in all four appearances for his national side - it was a surprise to see him benched against Leeds. Gyokeres found the back of the net against Poland and Bosnia, while also scoring in both encounters with Romania. 

Assuming Gyokeres starts midweek, this will be an ideal opportunity for him to try and lock down a starting role under Mikel Arteta, and prove he is up to standard.

Eberechi Eze is another player who has largely had to settle with a role from the bench this campaign, but he has typically played in midweek games.

Arsenal are looking a bit light on wide options, so Eze is likely to feature on the wing here. The former Crystal Palace man started against Napoli before the international break, and he committed two fouls. In his only other start of the season, he also landed this selection with one foul against Ipswich Town.

Eze is likely to play on the same flank as Dilane Bakwa on Tuesday night - he scored against Le Havre at the weekend, and is averaging 1.86 fouls drawn per 90 this season.

Hakon Haraldsson is another player who has been adept at drawing contact, and he has been one of Lille’s most consistent players this campaign. Tiago Santos has been fouled the most times for Lille this season with 15, but Haraldsson is not too far behind with 13 fouls drawn. 

Haraldsson is usually the player who Lille look to when they need to alleviate pressure - he likes getting on the ball in midfield, and is always looking to beat his man. The attacking midfielder has landed this selection in three of his last four starts, and he is averaging 2.37 fouls drawn per 90. Arsenal like to press aggressively in midfield areas, which bodes well for this selection.

Arsenal started their Champions League campaign with a 1-0 victory away against Napoli, as Martin Odegaard scored the decisive goal during the closing stages.

Mikel Arteta’s men went into the international break following a 3-0 defeat against Brighton, but they responded by completing an impressive comeback against Leeds at the weekend. That means the Gunners have won eight of their last nine matches across all competitions, maintaining their momentum after lifting the Premier League title last season.

Meanwhile, Lille were beaten 3-2 by Real Betis in their opening European match, despite taking the lead twice. They then squeezed past Le Havre last weekend, despite the visitors being reduced to ten men.

Arsenal look a lot stronger than Lille on paper here, and it is likely to be one-way traffic. The Gunners accrued eight corners in their opening Premier League match against Coventry, before also landing this selection against Chelsea. Last season, they had an average of 5.75 corners per game across all competitions, rising to 6.0 when playing at the Emirates. 

Set pieces remain a significant part of Arsenal’s attacking approach, so they typically look to utilise width when their opponents sit deep. The hosts should dominate proceedings, forcing Lille into extended spells of defending their box. That should bring corners into the game.

Ayase Ueda has made a strong start to life at Lille since arriving from Feyenoord, contributing three goals from just five appearances.

That includes getting on the scoresheet against Real Betis in his last Champions League appearance. The Japanese international is averaging 2.96 shots per 90 this season, which is the highest figure in the Lille squad. Even though that is based on a small sample size, it is worth noting that he had an average of 3.37 shots per 90 across all competitions for Feyenoord last season - he is adept at finding gaps in opposing defences.

Impressively, 42% of those efforts hit the target as well. Ueda will be Lille’s biggest threat in transition, and he will hope to exploit this Arsenal backline who have looked a bit shaky in defence.

Benjamin Andre has long been one of Lille’s most aggressive midfielders over the years, and he has recorded double-digit card counts in all seven seasons as a Lille player. That includes 11 yellows in 37 appearances across all competitions last season, and 15 in the campaign before that. 

This season, he has picked up one card in four appearances, but he is averaging 2.43 fouls per 90 in that time, which shows how his intense approach hasn’t changed. The Frenchman will have a tough task here trying to contain the Arsenal forwards, so this price stands out.

Martin Odegaard scored the winning goal against Napoli in Arsenal’s opening Champions League match, so he should be looking forward to this fixture.

The Norwegian international was one of the standout performers for Arsenal prior to the international break - he scored in four out of eight appearances across all competitions. Even though he didn’t score against Leeds last time out, he still played a massive role in the final third, and recorded a shot on target. 

Odegaard only scored one goal in 36 appearances across all competitions last season, but he looks revitalised this term. He was much more of a provider last season, contributing seven assists, and he will be the one pulling the strings again midweek.

Roma have been an entertaining side to watch under Gian Piero Gasperini, and they are battling near the top of the Italian top flight with four wins and two draws from their opening five matches.

They have scored 14 goals in that time. Even last season, Gasperini guided the Romans to a third-place finish, only behind Inter Milan and Roma, which shows how they are an incredibly competitive side now.

They have pulled off some impressive results already this season, including a 2-1 win against Atalanta, and a 2-2 draw against Inter. Over 2.5 has landed in four of their seven matches across all competitions this season. 

Goals have also been flying in when Real Madrid are playing - over 2.5 goals has landed in eight out of ten of their fixtures this term.

Roma are averaging 5.2 corners per game in Serie A this season, in addition to 18.7 shots per match. They landed this selection against Inter Milan, with 18 shots and four corners, and Atalanta.

Gasperini prefers a 3-4-3 system, and he wants his wingbacks to be positive and make overlapping runs. Roma always look to progress play through their wide players and send crosses into the box, which brings corners into the game. 

Real Madrid come into this clash as favourites, but this could be a tough night for them, especially at the Stadio Olimpico. The hosts are unlikely to sit back and absorb pressure, especially considering how Real Madrid have already lost two of their four away matches this season.

Paulo Dybala has made his return from injury recently, and he has been one of Roma’s most influential players in the final third. The Argentine international has accumulated 23 shots from seven appearances, with eight of those efforts hitting the target. He has also provided four assists, which is the highest in the Roma squad.

Dybala has been playing just behind Donyell Malen, in an inside forward role which has given him the freedom to find pockets of space in the final third. He is the designated free-kick taker for Roma, and could also be on penalty duties. Dybala had an injury-hit previous campaign, but he looks back to his best this term, and he will be hoping to make an impact against Real Madrid midweek.

Gianluca Mancini has benefitted from the back three system under Gasperini, as he has more cover defensively. Mancini likes to be aggressive in his challenges, and step out to try and contest duels.

He has committed ten fouls in seven appearances this season, averaging 1.62 fouls per 90. The Italian international will be playing on the same side as Vinicius Junior on Wednesday night, and that is a matchup to keep an eye on. 

The Brazilian is averaging 3.21 fouls drawn per 90 this season across all competitions, and he has earned a reputation for being a frustrating player to come up against.

Mancini has shown a tendency to lose his head at times - he picked up 12 yellow cards and one red in 45 appearances across all competitions last season.

Jude Bellingham is another player who has been adept at drawing contact for Los Blancos, and he should also find duels against Mancini when he drifts over to the left. The Englishman is averaging 3.17 fouls drawn per 90 this campaign, and he has drawn multiple free-kicks in eight of his nine appearances overall. 

Bellingham also had an average of 2.42 fouls drawn per 90 last season across all competitions - he is a strong carrier of the ball, and he sees plenty of involvement in midfield. Considering Roma are averaging 13.3 fouls per game this season, it looks like an excellent matchup for him to be fouled.

Liverpool made a steady start under Iraola prior to the international break, remaining unbeaten in seven games across all competitions. After starting positively against Man City at the weekend, it was a red card to Ryan Gravenberch which ultimately proved costly. After his dismissal, the visitors scored three times.

Liverpool have been effective on their travels so far, picking up seven points from three away games while also keeping two clean sheets. The Reds started their Champions League campaign with a 2-1 victory over Atletico Madrid, and they will hope to follow that up with another three points here.

LASK were beaten 2-0 by Rapid Wien at the weekend, meaning they have failed to win any of their last four matches across all competitions coming into this clash.

Even without some of their key attacking players, Liverpool should have more than enough attacking firepower to get the job done in Austria, and it is likely to be one-way traffic. Liverpool matches are averaging 9.9 corners this season, and their Champions League opener against Atletico Madrid saw a total of 12 corners. The Reds accounted for seven of those.

LASK have been just as effective at generating corners so far. In fact, they are averaging 7.1 corners per game across all competitions this season. They have been quite effective at getting to the byline, and they will have to be direct against Liverpool.

Bradley Barcola is still waiting for his first goal contribution since joining Liverpool over the summer, but this fixture presents an excellent opportunity for him. The Reds are missing key attacking personnel, so there is big pressure on the shoulders of the Frenchman. 

Barcola joined Liverpool after contributing 76 goals and assists across 152 appearances for PSG, so there is no doubt about his quality in the final third. He racked up 21 goals and 20 assists in his first full season at PSG, before adding another 13 goals and six assists last season. It has taken some time for him to find his feet this campaign, but this looks like a favourable matchup.

Florian Wirtz had a tough outing against Man City last time out, but with the Reds so depleted in forward areas, Iraola might have to stick with the German international.

After completing his big money move from Bayer Leverkusen, Wirtz managed just seven goals and eight assists in his first full season for Liverpool. So far this term, he has just one assist to his name, despite featuring in seven games. 

However, he is still averaging 2.25 shots per 90, which shows how he is still picking up promising shooting positions. This will be an ideal opportunity for him to break his duck and start re-building some confidence.

If LASK are going to pose a threat in the final third against Liverpool, Kasper Jorgensen will have to play a role. The Danish international has been incredibly active going forward for LASK this campaign, despite being listed as a right wingback on paper. He has recorded 29 shots in 12 appearances, averaging 2.82 shots per 90 across all competitions.

Even last season, he bagged seven goals in 32 league appearances for LASK, which shows just how important he is going forward. Jorgensen isn’t afraid to try his luck from distance, and he usually shoots as soon as the space opens up. That could be useful against Liverpool where chances will be rarer than usual.